I have been a care giver for 20 years. four kids and wife?

we have dealt with my wifes son trying to kill himself for 7 years. she could not deal with it or anything. i ended taking care of her sons problems, docs councilers insurance and all the running while having a 55 hour a week job.i have ended up making a very good wife for her. she is on 8 meds for dep. angxiety. she wants to goup north to a friends to get away from everything. this is running away from her problems and not dealing with them. right? i am also dealing with empty nest syndrome. didnt think there was such a thing. i am lost on what to do?